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administration, and therapeutic adaptability. Understanding its classical preparation principles alongside modern pharmaceutical concepts is essential for optimizing efficacy, stability, and patient compliance. Methods: A comprehensive literature search was conducted using classical Ayurvedic texts (Charaka Samhita, Sushruta Samhita, Ashtanga Hridaya) and modern databases including PubMed, Scopus, and Web of Science. Inclusion criteria encompassed studies on Churna pharmacology, preparation methods, standardization, and clinical applications. Exclusion criteria were formulations not recognized in classical texts or lacking scientific validation. Data were analyzed thematically to integrate traditional knowledge with modern dosage form relevance. Results: Classical Churna preparations emphasize selection, purification, and trituration of raw herbs to achieve uniform particle size and stability. Modern analytical studies demonstrate that particle size reduction enhances dissolution, bioavailability, and therapeutic efficacy. Microencapsulation, standardization of moisture content, and incorporation into tablets or capsules bridge traditional and modern dosage forms. Pharmacological studies corroborate efficacy in digestive, metabolic, respiratory, and neurological disorders. Discussion: Integration of classical principles with contemporary pharmaceutical technologies ensures safety, reproducibility, and enhanced patient compliance. Gaps remain in standardization, quality control, and clinical validation of Churna formulations. Future research should focus on mechanistic studies, modern delivery systems, and regulatory frameworks for global acceptance. Conclusion: Churna Kalpana exemplifies the convergence of traditional wisdom and modern pharmaceutical science. Optimizing these formulations through standardization and advanced delivery methods can enhance therapeutic outcomes and integrate Ayurveda into contemporary healthcare.

KEYWORDS: Ayurveda, Churna, dosage form, pharmacology, standardization