Become A Member

Introduction: Abhraka Bhasma, a herbo-mineral preparation derived from mica, is one of the most esteemed formulations in Ayurveda. Traditionally, it is prepared through a series of Shodhana (purification) and Marana (calcination) processes, rendering mica into a bioabsorbable nano-structured form. It has been widely indicated in Rasayana therapy, respiratory disorders, anemia, infertility, and neurodegenerative conditions. In recent decades, modern pharmacological studies have attempted to validate these traditional claims. Methods: A systematic literature search was conducted using Ayurvedic classical texts (Rasatarangini, Rasaratna Samuccaya, Bhaishajya Ratnavali), scientific databases (PubMed, Scopus, Web of Science, AYUSH Research Portal), and peer-reviewed journals. Inclusion criteria were studies on classical references, experimental pharmacology, toxicity evaluations, and clinical trials on Abhraka Bhasma. Exclusion criteria included non-peer-reviewed sources and anecdotal reports. Results: Classical texts describe more than 70 formulations containing Abhraka Bhasma, prescribing it for Kasa (cough), Shwasa (asthma), Panduroga (anemia), and as a potent Rasayana. Modern studies reveal its antioxidant, adaptogenic, anti-inflammatory, hematinic, immunomodulatory, neuroprotective, and reproductive health–enhancing properties. Toxicological studies suggest safety at therapeutic doses, while nano-scale characterization has demonstrated particle sizes <100 nm, indicating higher bioavailability. Clinical studies, although limited, support its use in chronic respiratory and hematological disorders. Discussion: Comparative analysis highlights concordance between classical claims and modern pharmacological findings. However, gaps remain in large-scale randomized clinical trials, standardization protocols, and long-term safety evaluations. Conclusion: Abhraka Bhasma represents a unique example where traditional wisdom aligns with modern pharmacology. Further multidisciplinary research integrating Ayurveda, nanotechnology, and biomedicine may open new therapeutic avenues.

KEYWORDS: Abhraka Bhasma, Ayurveda, classical indications, pharmacological studies, Rasayana